See also Warning section.

Read the Medication Guide provided by your pharmacist before you start taking oxycodone/acetaminophen and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

Take this medication by mouth as directed by your doctor. You may take this drug with or without food. If you have nausea, it may help to take this drug with food. Ask your doctor or pharmacist about other ways to decrease nausea (such as lying down for 1 to 2 hours with as little head movement as possible).

Avoid eating grapefruit or drinking grapefruit juice while using this medication unless your doctor or pharmacist says you may do so safely. Grapefruit can increase the chance of side effects with this medicine. Ask your doctor or pharmacist for more details. Percocet

If you are using a liquid form of this medication, use a medication measuring device to carefully measure the prescribed dose. Do not use a household spoon because you may not get the correct dose.

The dosage is based on your medical condition and response to treatment. Do not increase your dose, take the medication more frequently, or take it for a longer time than prescribed. Properly stop the medication when so directed. Percocet

Pain medications work best if they are used as the first signs of pain occur. If you wait until the pain has worsened, the medication may not work as well.

If you have ongoing pain (such as due to cancer), your doctor may direct you to also take long-acting opioid medications. In that case, this medication might be used for sudden (breakthrough) pain only as needed. Other pain relievers (such as ibuprofen, naproxen) may also be prescribed with this medication. Ask your doctor or pharmacist about using oxycodone safely with other drugs. Percocet

Suddenly stopping this medication may cause withdrawal, especially if you have used it for a long time or in high doses. To prevent withdrawal, your doctor may lower your dose slowly. Tell your doctor or pharmacist right away if you have any withdrawal symptoms such as restlessness, mental/mood changes (including anxiety, trouble sleeping, thoughts of suicide), watering eyes, runny nose, nausea, diarrhea, sweating, muscle aches, or sudden changes in behavior. Percocet

When this medication is used for a long time, it may not work as well. Talk with your doctor if this medication stops working well.

Though it helps many people, this medication may sometimes cause addiction. This risk may be higher if you have a substance use disorder (such as overuse of or addiction to drugs/alcohol). Take this medication exactly as prescribed to lower the risk of addiction. Ask your doctor or pharmacist for more details.

Tell your doctor if your pain does not get better or if it gets worse.  Percocet

How does this medication work? What are its effects?

This combination medication contains 2 active ingredients: oxycodone and acetaminophen. Acetaminophen belongs to a group of medications called analgesics (painkillers) and antipyretics (medicines that lower a fever). Oxycodone belongs to the group of medications called narcotic pain relievers . This medicine is used to relieve moderate to moderately severe pain, including conditions associated with fever. This medication should only be used when other non-narcotic analgesics are not effective or not tolerated. Percocet

Your doctor may have suggested this medication for a condition that is not listed in this medication information article. Also, some forms of this medication may not be used for all of the conditions mentioned in this article. If you haven’t discussed this with your doctor yet, or if you’re not sure why you’re taking this medication, check with your doctor. Do not stop taking this medication without consulting your doctor first. Percocet

Do not give this medicine to anyone, even someone who has the same symptoms as yours. This medicine could harm people for whom it was not prescribed.